RFX4 antibody (Middle Region)

Catalog No. ABIN1108876

This Rabbit Polyclonal antibody specifically detects RFX4 in WB. It exhibits reactivity toward Rat, Human, Mouse and Dog.

Quick Overview for RFX4 antibody (Middle Region) (ABIN1108876)

Target: RFX4 (Regulatory Factor X 4 (RFX4))

Reactivity: Rat, Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFX4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RFX4 Antibody

Binding Specificity: Middle Region

Sequence: NVDLNSITKQ TLYTMEDSRD EHRKLITQLY QEFDHLLEEQ SPIESYIEWL

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogen: The immunogen for anti-RFX4 antibody: synthetic peptide directed towards the middle region of human RFX4.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for RFX4

Target: RFX4 (Regulatory Factor X 4 (RFX4))

Alternative Name: RFX4

Background: RFX4 is a transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX4 is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. RFX4 may be a transcriptional repressor rather than a transcriptional activator.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.Synonyms: NYD-SP10, Regulatory factor X 4, Testis development protein NYD-SP10, Transcription factor RFX4

Gene ID: 5992

NCBI Accession: NP_002911